Our laboratory's research focuses on the characterization and function of extracellular vesicles (EVs) derived from and mesenchymal stem cells (MSC-EVs). We were among the first teams in the world to study the characteristics and functions of multiple myeloma(MM)-EVs, discovering that leukemia cell-derived EVs may play a role in the pathogenesis of leukemia. Recent studies have shown that MSC-EVs contain "young" factors that can improve age-related degenerative changes and functions in multiple organs. We have also collaborated on the development of efficient EVs enrichment techniques and fluorescence molecular tomography (FMT)-based in vivo tracking techniques. Additionally, our engineered EVs targeting angiogenesis and CD38-ARM-EVs have shown potential as effective treatments for age-related pulmonary fibrosis. Two of our achievements were accepted as posters at the 2024 ISEV Annual Meeting.